The surface which could clean it by itself and combat with the immune response of the body could increase the life of biosensors inside the human body.
The sensors implanted beneath the skin give continuous information therefore this technique is considered as the easiest and simplest way to get reports on chronic diseases like diabetes.
The implanted sensors continue working in the right manner as long as its surface remains clean. But as it is not the part of the body and the body treats it as it is and produces antibodies against this outsider. This is actually called as the immune response; which is actually defence reaction against an invading substance.
This immune system usually fails to destroy the sensors, if it happened body reacts in other way. In this way, specialist cells fibroblasts move in and start developing a tissue layer to form a capsule shaped body around the sensor; this layer effects the sensor greatly and makes its sensitivity less effective.
Rebecca Gant working at Texas A&M University in College Station made a research with his colleagues and succeeded in developing a new thing called self-cleaning membrane. She positively thinks that she can cope with the problem and this invention would help in combating the growth of fibrous tissue. This will be achieved by coating the implanted sensor with this newly invented self-cleaning membrane.
This membrane is actually a hydrogel. Its properties depend on the temperature. When the temperature is below 34 °C it switches to hydrophilic state having the characteristics of absorbing water and swelling whereas in the temperature above 34 °C it behaves and shifts to hydrophobic state with totally opposite behavior in which it releases water and shrinks.
The researchers say that this behavior of the membrane with the temperature in its properties of swelling and shrinking is would move away and get rid of the cells that have become attached to the surface.
This was a just claim it needed practical demonstration for that they placed it in a mouse fibroblast cell culture. This experiment was given a time of full night keeping it at 37 C; which is the normal body temperature. In the morning the researchers saw that it started working; the fibroblast was forming a layer around the hydrogel and was going to encapsulate it.